Orthogonal upconversion mimicking Nd-Mn heterometallic nanocomposite for dual NIR responsive self-amplifying photodynamic/chemodynamic therapy.
Shallow tissue penetration of excitation light remains the most persistent barrier to effective photodynamic therapy (PDT), compounded further by tumour hypoxia and elevated glutathione (GSH). Herein, we report a rationally engineered core-shell nanoplatform comprising a Mn-centred porphyrinic metal-organic framework c...