Open access
Aug 2026
Control of breast cancer patient-derived xenografts by CD70-targeted HIT-CAR T cells
CAR T cell therapies have shown clinical success in several tumor types, though not in breast cancer, for which advanced stages remain incurable. CD70 is expressed in a broad range of solid tumor types and is emerging as a molecular target for CAR T cells in renal and ovarian malignancies. Here we show that a subset of...
P. Lindenbergh, Vinagolu K. Rajasekhar, I. Linkov et al.
· Frontiers in Immunology · 0 citations