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Author

S. Hannou

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Open access Sep 2026

Manganese availability determines insulin sensitivity by enhancing Akt activity

Manganese is established as a physiologically regulated cofactor for Akt and position metal bioavailability as a previously unrecognized layer of insulin signaling control and suggests a molecular explanation for the glucose-lowering effects of manganese observed in humans.

J. Gamarra, Sei Higuchi, Timothy L. Yuan et al. · 0 citations
Open access Oct 2026

Manganese availability determines hepatic insulin sensitivity by enhancing Akt activity.

Manganese is established as a physiologically regulated cofactor for Akt and position metal bioavailability as a previously unrecognized layer of insulin signaling control and suggests a molecular explanation for the glucose-lowering effects of manganese observed in humans.

J. Gamarra, Sei Higuchi, Timothy L. Yuan et al. · 0 citations

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