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Open access Aug 2026

Blood metal signatures and their association with Alzheimer’s disease risk and cognitive decline in an Egyptian cohort

Alzheimer’s disease (AD) is a multifactorial disease in which environmental exposures may contribute to disease risk. This study aimed to investigate associations between blood concentrations of arsenic, lead, mercury, and lithium with AD risk and cognitive performance in an Egyptian cohort. We conducted a cross-sectio...

Mai Othman, Eman Khedr, G. Fawi et al. · 0 citations
Open access Aug 2026

Translating cellular aging clocks into disease risk prediction

Ding et al. mapped over 7,000 plasma proteins to more than 40 cell types and developed machine learning aging clocks across 60,000 individuals, demonstrating that cell-type-specific biological aging is heterogeneous, measurable from blood alone, and powerfully predictive of neurodegenerative disease, cancer, and mortal...

Shimaa A. Heikal, Mohamed Salama · 0 citations

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