Author

S. Huntley

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Sep 2026

The Orphan Histidine Kinase TodK Influences Myxococcus xanthus Multicellular Development by Inactivating the CRP/Fnr Homolog, MrpC.

Environmental bacteria have abundant signaling systems wired into complex gene regulatory networks to adapt to fluctuating conditions. In Myxococcus xanthus, starvation triggers a developmental program (specialized biofilm) that produces spore-filled multicellular fruiting bodies surrounded by a distinct quiescent stat...

Christopher Mataczynski, Maike M. Glaser, S. Huntley et al. · Molecular Microbiology · 0 citations

Open access Jul 2026

The orphan histidine kinase TodK controls Myxococcus xanthus biofilm development by inactivating the CRP/Fnr homolog, MrpC

Findings establish TodK as a modulator of developmental progression and demonstrate how quantitative phenotyping approaches can reveal biologically meaningful functions for orphan histidine kinases whose mutant phenotypes might otherwise appear subtle.

Christopher Mataczynski, Maike M. Glaser, S. Huntley et al. · bioRxiv · 0 citations