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Open access Sep 2026

In utero barcoding of mouse mesoderm reveals the clonal architecture of organ mesenchyme

The mesoderm coordinates organogenesis and generates the cardiovascular, visceral and musculoskeletal systems, yet in mammals this germ layer is difficult to access, impeding its genetic manipulation and study. Here, we establish embryonic day (E) 7.5 exocoelomic cavity nano-injection as a scalable route for selective...

Jing-Yan He, J. Lorentz, A. Corbat et al. · 0 citations
Open access Sep 2026

Atlas of cell types and regulatory elements underlying human facial diversity.

Human genetic diversity generates an astonishing variety of facial shapes, and craniofacial anomalies rank among the most common birth defects. Identifying the cellular mechanisms that mediate the genome's influence on facial variation remains a challenge. Here we created a multimodal facial atlas across embryonic week...

A. Erickson, Yaakov Gershtein, Rozalina Galimullina et al. · 0 citations

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