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S. Isakoff

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Open access Sep 2026

Actionable genetic landscape and dynamics in circulating DNA from 12,827 patients with metastatic breast cancer

Plasma cell-free DNA (cfDNA) is a sensitive, noninvasive tool for monitoring the genomic landscape, heterogeneity, and evolution of cancer, aggregating genetic information from multiple metastatic sites. Here, we study 15,564 cfDNA samples from 12,827 patients with metastatic breast cancer (MBC). We classify sample...

I. Leshchiner, A. Medford, J. Cha et al. · 0 citations

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