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Author

S. James

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Sep 2026

Paclitaxel-Coated Devices in Patients With Chronic Limb-Threatening Ischemia and Tissue Loss Undergoing Infrainguinal Endovascular Revascularization: Insights From the SWEDEPAD-1 Trial.

BACKGROUND Patients with chronic limb-threatening ischemia and tissue loss (Rutherford 5-6) are at high risk of major amputation. Drug-coated technologies are effective in coronary interventions, but their impact on limb outcomes in advanced ischemia remains uncertain. We evaluated whether drug-coated devices improve l...

Fredrik Sellgren, Mårten Falkenberg, M. Andersson et al. · 0 citations
Open access Jul 2026

Extracellular vesicle secretome from mesenchymal stromal cells prevents post-ischemic heart failure by targeting cardiac fibrosis.

A clinically approved PDGFRβ-targeted PET-imaging platform for longitudinal assessment of fibrotic activity in STEMI patients and preliminary observations suggest that myofibroblast activation persists for up to 2 months after STEMI in selected patients establish a translational therapeutic-diagnostic framework for ind...

Karl-Henrik Grinnemo, Ken Braesch-Andersen, Johan O. Wedin et al. · 1 citation

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