Serum IgM and Soluble IL-2 Receptor as Predictors of Granulomatous-Lymphocytic Interstitial Lung Disease in CVID
Granulomatous-lymphocytic interstitial lung disease (GLILD) develops in 10–30% of patients with common variable immunodeficiency (CVID) as a consequence of immune dysregulation. Therefore, immunoglobulin (Ig) M, produced by apoptosis-resistant plasmablasts in extrafollicular sites in the lungs, and serum soluble in...