Author

S. K. Forslund-Startceva

3 papers indexed here

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Open access Sep 2026

Systematic quantification and removal of host DNA contamination in 16S rRNA gene sequencing.

16S ribosomal RNA (rRNA) gene sequencing is a standard tool for microbial community analysis. Challenges can occur, particularly in low-biomass samples, when host DNA triggers off-target amplification. Low-biomass microbiome studies are particularly vulnerable to contamination from host DNA, which can obscure microbial...

T. Birkner, Theda Ulrike Patricia Bartolomaeus, V. McParland et al. · Quantitative Biology · 0 citations

Open access Oct 2026

Functional microbiome shifts are associated with neuroinflammatory outcomes under dietary interventions in multiple sclerosis

Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system. While disease-modifying therapies can reduce relapse rates, their limitations have spurred interest in adjunctive approaches such as fasting and ketogenic diets (FD, KD). In a randomized controlled trial, participants with relap...

Friederike Gutmann, L. S. Bahr, Ulrike Bruning et al. · Scientific Reports · 0 citations

Open access Aug 2026

metadeconfoundR: Covariate analysis of high-dimensional cross-sectional omics data

This work benchmarked metadeconfoundR against state-of-the-art methods for identifying biomarkers using simulated ground truth derived from microbiome data, and demonstrated its ability to disentangle confounding effects while preserving statistical power.

T. Birkner, Chia-Yu Chen, Morgan Essex et al. · Bioinformatics Advances · 0 citations