Ionic Liquid-Integrated Interpenetrating Polymer Hydrogel for Injectable, Self-Healing, and Stimuli-Responsive Co-Delivery of Protein and Chemotherapeutic Agents in Breast Cancer Therapy.
A stimuli-responsive, multifunctional polymeric hydrogel is developed by incorporating biocompatible choline-lineolate ionic liquid into a sodium alginate and polyvinyl alcohol and polyvinyl alcohol matrix for enhanced co-delivery of doxorubicin and zein in localized breast cancer treatment.