Author

S. Kanagasingam

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Open access Oct 2026

TMEM106B analysis in diverse cohorts suggests no association with Parkinson's disease risk

Recent evidence suggests that TMEM106B expression is reduced in the brains of patients with Parkinson's disease (PD). However, an association between rare genetic variants in TMEM106B and PD risk has not been previously established. In this work, we investigated the association between rare TMEM106B variants and PD ris...

H. M. Chaparro Solano, S. Kanagasingam, Z. Gan-Or et al. · medRxiv · 0 citations

Open access Aug 2026

Rare-Variant Burden Analysis of Dystonia Genes in Parkinson's Disease.

BACKGROUND Dystonia frequently coexists with Parkinson's disease (PD), yet the extent of genetic overlap remains insufficiently explored. OBJECTIVE The aim was to examine whether rare variants in dystonia-related genes are associated with PD or early-onset PD (EOPD). METHODS We curated 44 dystonia-related genes usi...

S. Kanagasingam, S. C. Parlar, Lang Liu et al. · Movement Disorders · 0 citations