Author

S. Kebir

3 papers indexed here

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Aug 2026

Feasibility of First-line Lomustine-Temozolomide (CCNU/TMZ) in Elderly Patients with MGMT-methylated Glioblastoma: A Multicenter Retrospective Cohort Study

The CeTeG/NOA-09 trial showed improved survival with lomustine (CCNU) plus temozolomide (TMZ) over TMZ alone in O6-methylguanine-DNA-methyltransferase (MGMT) promoter-methylated glioblastoma patients aged 18-70 years. Data on feasibility, tolerability and outcomes in patients over 70 receiving this regimen are la...

Julia Scheuble, T. Zeyen, Matthias Schneider et al. · Neuro-Oncology Practice · 0 citations

Review Open access Sep 2026

Machine learning models for adverse drug reaction prediction. A systematic review and three-level multilevel meta-analysis

Background Adverse drug reactions (ADRs) are a leading cause of preventable hospitalization, yet the dominant pharmacovigilance paradigm remains reactive. Machine learning (ML) offers a data-driven alternative, but the evidence base has not been formally meta-analyzed under clinically realistic inclusion criteria and a...

G. Cappello, C. Oster, T. Schmidt et al. · Frontiers in Pharmacology · 0 citations

Open access Sep 2026

A multicenter analysis of prognostic factors for patients undergoing re-irradiation for recurrent glioblastoma

Re-irradiation (re-RT) has gained popularity in the treatment of recurrent or progressive glioblastoma (rGBM) after first-line treatment. However, uncertainties regarding optimal treatment dose, fraction size and target volume definition remain. In this multicenter analysis of the Western German Cancer Center (WT...

N. Pepper, M. Guberina, C. Poettgen et al. · Neuro-Oncology Advances · 0 citations