Structure-Guided Identification of 2-Arylbenzothiazole as disruptors for the Oncogenic MTDH-SND1 Protein-Protein Interaction.
2-arylbenzothiazoles are established as a promising chemotype for MTDH-SND1 PPI inhibition and provide a validated computational-to-experimental framework for discovering and optimizing MTDH-directed therapeutics.