S. Kirin

Pyrimidine- and furo[2,3-d]pyrimidine-isoxazole hybrids and their Re(i) tricarbonyl complexes with antiproliferative activity against hematological malignancies

Pyrimidine and furo[2,3-d]pyrimidine derivatives have emerged as promising anticancer agents that act through multiple mechanisms, including modulation of downstream signaling pathways such as a JAK2/STAT3 cascade. Herein, we report the synthesis of novel pyrimidine- and furo[2,3-d]pyrimidine-isoxazole hybrids via base...