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Open access Aug 2026

Colon-targeted oral delivery of melatonin for regulating macrophage activity and intestinal barrier in ulcerative colitis

Background Despite its promising therapeutic potential, inefficient site-specific targeting and complex fabrication processes hinder the clinical translation of oral melatonin therapy for ulcerative colitis (UC). Herein, we present Melatonin-Eudragit-Thioketal polymer-based Assembly (META), a dual pH/ROS-responsive ora...

Nhu-Nam Nguyen, Yoojin Seo, T. Nguyen et al. · 0 citations

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