Gene therapy represents a crucial frontier in modern medicine for brain diseases; however, a significant obstacle hinders its progress. The immense difficulty of therapeutic molecules that deliver to the brain should be in a safe and effective way. The challenge is that blood brain barrier (BBB) blocks most drugs from...
H. Hashemi, Babak Mikaeeli Kangarshahi, Ghasem Takdehghan et al.· Discover Neuroscience· 0 citations
The present study emphasises niosomes as versatile nanocarriers with great potential for the next generation of drug delivery and describes the major challenges that need to be overcome for further clinical and commercial translation.
Khashayar Khodaverdi, S. M. Naghib, Ghasem Takdehghan et al.· BioNanoScience· 0 citations
A new Triple-Stimuli Release Model is presented that provides a computational experimental bridge to expedite preclinical validation while mathematically forecasting concurrent release kinetics and how well molecular dynamics simulations and artificial intelligence combine to forecast toxicity, drug-carrier interaction...
H. Hashemi, Aref Zahiri Ghareh Mosa, Ketevan Tavamaishvili et al.· Discover Applied Sciences· 0 citations
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