Background Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous disease influenced by genetic and environmental factors. However, the interactions between COPD risk genes and their collective role in COPD susceptibility remain largely elusive. We hypothesize that the protein-protein interaction (PPI...
D. Deritei, H. Inuzuka, Cheng-Yue Zhang et al.· bioRxiv· 0 citations
When intestinal stem cells (ISCs) are damaged, other epithelial cells de-differentiate to restore the ISC compartment. Immune, nerve and lymphatic endothelial cells contribute signals that promote this response, but it is unclear whether or how the native mesenchymal niche senses and responds to ISC loss. In homeostasi...
Neil McCarthy, Camila Mendez Jimenez, Guodong Tie et al.· Development· 0 citations
Alterations in metabolomic profiles of COPD and IPF suggested shared dysregulation of several lipids, however, some metabolites pointed to disease-specific differences.
Aldric Rosario, N. Prince, S. Madha-Krause et al.· Metabolomics· 0 citations
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