Author

S. Médina Villalon

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Open access Sep 2026

How to Recognize and Manage Missing Key Electrodes in Defining the Epileptogenic Zone

Identifying and localizing the epileptogenic zone (EZ) is the cornerstone of successful epilepsy surgery, as it directly determines surgical efficacy and patient outcomes. Stereoelectroencephalography (SEEG) has emerged as a transformative tool for pinpointing the EZ, offering precise 3-dimensional recordings of seizur...

Hussam Shaker, S. Médina Villalon, J. González-Martínez et al. · Epilepsy Currents · 0 citations

Open access Sep 2026

Higher-order interdependencies of the epileptogenic network in presurgical resting-state fMRI

Drug-resistant focal epilepsy (DRFE) is understood as a complex brain network disorder. As a result, conventional pairwise functional connectivity may fail to capture the higher-order interactions between groups of epileptogenic regions. We applied multivariate information theory to stereotactic electroencephalography-...

Jacob Knight, Matteo Neri, J. Makhalova et al. · bioRxiv · 0 citations

Open access Jul 2026

Integrating multiparametric MRI with intracranial electrophysiology characterizes thalamic pathology in focal epilepsy

Combining quantitative sodium, structural, and functional 7 Tesla MRI with stereotactic electroencephalography (SEEG) and clinical characterization to establish a multimodal framework for investigating thalamic involvement in drug-resistant focal epilepsy and establishes a framework for characterizing pathological netw...

R. Haast, J. Makhalova, L. Gauer et al. · medRxiv · 0 citations