Open access
Sep 2026
Association of Three HIF‐1α Genotypes With Susceptibility and Severity of Chronic Kidney Disease
ABSTRACT Hypoxic signaling is a critical factor in the pathogenesis of Chronic Kidney Disease (CKD). Hypoxia‐Inducible Factor 1 (HIF‐1) is a transcription factor that is highly expressed in the kidney and is associated with renal tubular hypoxic adaptation. Variation in the HIF‐1α subunit gene has been associated with...
Hanifa Aktar, Shahrzad Ashena, Mohammad Sanaei Ardekani et al.
· Clinical and Translational S... · 0 citations