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Author

S. Mukkavalli

2 papers indexed here

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Open access Sep 2026

The role of CHAMP1 in chromatin-mediated DNA damage repair.

Defects in the replication stress response are major drivers of cancer development and present key targetable vulnerabilities that can be exploited for anti-cancer therapy. Recent studies have identified CHAMP1 as a novel DNA damage repair factor with roles in double-strand break repair and the replication stress respo...

Felix Y. Zhou, Jinal A. Patel, Aindri H. Patra et al. · 0 citations
Open access Aug 2026

The p97 adaptor p47/NSFL1C is necessary for stress granule dissolution after heat stress.

Stress granules form in response to diverse cellular perturbations to sequester translation components until the stress is resolved. Stress granules are composed of RNA-protein assemblies in membrane-delimited structures and must be rapidly disassembled to release components to allow translation to resume. Disassembly...

Michelle A. Johnson, R. Khanna, S. Mukkavalli et al. · 0 citations

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