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S. Muthu

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Review Open access Sep 2026

AO Spine Clinical Practice Recommendations: When to Operate in Lumbar Disc Herniation

Study Design Literature review with consensus clinical recommendations. Objective To review key studies on surgical vs. non-operative treatment for lumbar disc herniation (LDH) and present recommendations for how the practicing clinician should use this evidence. Methods Two randomized controlled trials (RCTs), two RCT...

G. Vadalà, L. Ambrosio, Xiao-Long Chen et al. · 0 citations
Review Open access Sep 2026

Spatial Multi-Omics Advances in Osteoarthritis: From Molecular Landscapes to Precision Medicine

Osteoarthritis (OA) is a pervasive, multifactorial joint disorder with an escalating global prevalence, yet it remains without effective disease-modifying therapies. Current research and clinical management are hindered by a reliance on traditional bulk-omics and imaging modalities that fail to capture the profound mol...

M. Jeyaraman, Naveen Jeyaraman, Swaminathan Ramasubramanian et al. · 0 citations
Review Open access Sep 2026

Recommendations of the International Consensus Meeting (ICM) 2025 on Spinal Infections: Part A Pyogenic Spondylodiscitis

Study Design Systematic review with guidelines. Objective To develop evidence-based, globally applicable recommendations for diagnosis and management of pyogenic spondylodiscitis (PSI) as a part of the International Consensus Meeting (ICM) 2025 on Spinal Infection. Methods A multi-phase consensus process combined syste...

S. Rajasekaran, S. Muthu, Gnanaprakash Gurusamy et al. · 0 citations
#diffusion models Review Open access Sep 2026

Fragility fracture risk prediction using quantitative magnetic resonance and Vertebral Bone Quality scoring beyond density.

Assessment of quantitative MRI and VBQ/modified VBQ into predictive models enables opportunistic, radiation-free screening and more precise fracture risk assessment, bridging the gap between bone quantity and quality for improved prevention and management of fragility fractures.

Sanjith Manian, Arunagiri Gunasekar, Naveen Jeyaraman et al. · 0 citations

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