High reelin expression may explain why a subgroup of entorhinal cortex neurons functions as an initial nucleation site of Alzheimer’s disease
The entorhinal cortex (EC) plays a crucial role in memory functions. Long before the clinical symptoms of Alzheimer’s disease (AD) emerge, it has already undergone significant degeneration, making it a primary site for the onset of the disease. The reasons for this remain elusive. Layer II (LII) neurons of the anterola...