The potential of astaxanthin in reducing lithium-induced neuroinflammation: Inhibitory effects on the NF-κB pathway.
BACKGROUND Lithium (LIT) can induce neurotoxicity through multiple mechanisms, including oxidative stress, neuroinflammation, and dysregulation of neuronal survival and cell death pathways. Astaxanthin (AST) is a xanthophyll carotenoid with potent antioxidant and anti-inflammatory properties and can scavenge reactive o...