Importance Psychiatric disorders are a major source of disability and premature mortality worldwide. Advances in genomics have clarified parts of their genetic architecture, prompting questions about whether genomic information can inform preventive strategies for psychiatric disorders in clinical practice. In this Per...
K. Musliner, Eva C. Schulte, G. Breen et al.· JAMA psychiatry· 0 citations
Background: Suicide is a major public health concern and a highly complex, heterogeneous phenotype. Increasing evidence implicates epigenetic mechanisms, particularly DNA methylation (DNAm), in suicidal behavior. Methods: Building on previous epigenome-wide association studies (EWASs), we conducted the largest EWAS to...
M. Acosta-Díez, M. Zafrilla-López, C. Barrot-Feixat et al.· medRxiv· 0 citations
Findings suggest that part of SCZ liability reflects genetic susceptibility to SUDs with potential implications for patient stratification and clinical management.
S. Aranda, D. Koller, S. Papiol et al.· medRxiv· 0 citations
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