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Open access Aug 2026

Heterogeneity in pre-vaccination population immunity can contribute to variability in vaccine effectiveness estimates

Vaccine effectiveness (VE) estimates can vary widely between years and populations, even for the same vaccine. Estimated VE is known to be sensitive to susceptible depletion and differences in pre-vaccination infection risk between vaccinated and unvaccinated populations. However, how variation in pre-vaccination risk...

A. Pillai, S. Park, M. Lipsitch et al. · 0 citations
Open access Sep 2026

A within-host-informed event-time framework linking epidemiological delay distributions

Understanding when and how pathogens spread from person to person is fundamental to characterizing transmission, interpreting surveillance data, and designing effective control measures. Yet key epidemiological delays--including the latent period, incubation period, generation interval, and serial interval--are difficu...

N. Jamieson, S. Park, K. Ainslie et al. · 0 citations

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