Open access
Sep 2026
A novel homozygous DLGAP5 splice-site variant in a woman with oocyte maturation arrest and recurrent IVF failure: a case report
Oocyte maturation arrest (OMA) is a rare cause of female infertility characterized by impaired oocyte maturation and recurrent failure of assisted reproductive technologies. Recent studies have identified DLGAP5 as a critical regulator of meiotic spindle assembly, with biallelic variants causing oocyte maturation d...
P. Jacob, Deepa Bhat, Adithya G. Urs et al.
· Frontiers in Genetics · 0 citations