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Author

S. Pchelina

2 papers indexed here

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Open access Oct 2026

Pharmacogenetic profile of the efficacy of agomelatine for stabilizing remission in patients with alcohol dependence and comorbid depressive disorders: results of a double-blind, randomized, placebo-controlled study

Alcohol dependence (AD) and depressive disorders (DD) exhibit a high level of comorbidity, significantly complicating treatment and worsening the clinical prognosis. The search for drugs that target the common pathogenetic mechanisms of these comorbid conditions is relevant. One such drug is agomelatine: an MT1 and M...

A. Kibitov, A. Ulitina, E. G. Vershinina et al. · 0 citations
Open access Jul 2026

Decreased expression of the PPARG, ADIPOQ, and SLC2A4 genes in subcutaneous adipose tissue in bariatric patients with morbid obesity and type 2 diabetes mellitus

The development of T2DM on the basis of obesity and BMI of more than 35 kg/m 2  is associated with reduced expression levels of the PPARG, ADIPOQ, LEP, LEP and SLC2A4 genes in SAT and VAT, and changes in gene expression in obesity were associated with a decrease in adiponectin and an increase in leptin serum concentra...

V. Miroshnikova, K. Dracheva, M. Grunina et al. · 0 citations

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