Open access
Sep 2026
10d, a Pyridoquinoxaline-Based P-Glycoprotein Inhibitor, Exacerbates MPTP-Induced Neurotoxicity in PC12 Cells
Efflux pumps are essential components of cellular detoxification mechanisms, regulating the intracellular accumulation of xenobiotics and endogenous compounds. Among them, P-glycoprotein (P-gp) plays a role in protecting the brain from potentially toxic molecules, and alterations in its function have been associated wi...
Claudia Cannas, G. Rocchitta, Antonio Carta et al.
· Current Issues in Molecular... · 0 citations