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S. Pricl

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Open access Sep 2026

Dissecting affinity determinants of benzotriazine-based ligands at sigma-1 receptor: a multilevel molecular dynamics analysis.

The sigma-1 receptor (S1R) is a chaperone protein involved in several physiological and pathological processes and represents an attractive target for the development of neuroactive and anticancer agents. Among S1R ligands, 3,3-disubstituted 3,4-dihydro-1,2,4-benzotriazines constitute a pharmacologically relevant but m...

M. Tonelli, Valeria Francesconi, Bruno Tasso et al. · 0 citations
Open access Jul 2026

CP32, a novel anti-oomycete cyclic peptide, interferes with cell-wall deposition in Phytophthora infestans.

CP32 is identified as a promising, targeted anti-oomycete agent with a unique mode of action, targeting the P. infestans cell wall, representing a valuable contribution to the development of sustainable strategies for the control of late blight.

Demetrio Marcianò, S. Rosa, Elena Marone Fassolo et al. · 0 citations

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