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Sep 2026

Abstract B129: Repurposed T-Box-Targeting Drug in Liposomal Formulation Shows Synergistic Efficacy Against PDAC

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers, largely due to late diagnosis, limited therapeutic response, and its dense desmoplastic stroma, which limits drug penetration. To address the need for more effective treatments, we investigated a repurposed small-molecule inhibitor targ...

Susan Immanuel, Serala Karabo, S. Prince et al. · 0 citations
Review Open access Sep 2026

Integrating artificial intelligence across the cancer drug discovery pipeline using a design-test-refine workflow

Robust validation across increasingly complex cancer models is required and it is proposed that AIDD should be used to prioritize testable treatment predictions, to form a holistic design-test-refine workflow.

Jin-Ming Bai, Jessica Sarah Faure, Tawfeeq Ahmed Khalfe et al. · 0 citations

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