Open access
Aug 2026
34 Therapeutic Targeting of the SLC7A11-GCLM-GPX4 Axis Sensitizes Glioblastoma to Ferroptosis and Associates with Poor Survival
The GPX-4/GCLM axis, which balances redox, is highly expressed and crucial for GBM cell survival and aggressive biological behavior and may be a valuable adjunct to diagnosis, as demonstrated by RSL3, FIN56, and BSO.
M. Behera, S. Purkait, Amit Ghosh et al.
· Neuro-Oncology · 0 citations