Rotenone Exposure in Zebrafish Parkinson's Disease Model Reveals NURR1-TOP2B Dysregulation and Gut-Brain Axis-Associated Pathology.
Parkinson's disease (PD) is a progressive neurodegenerative disorder in which early gastrointestinal dysfunction and oxidative stress are increasingly implicated through the gut-brain axis. Zebrafish (Danio rerio) offer a tractable model for PD research; However, to our knowledge, there is currently no consensus on the...