Author

S. Raran-Kurussi

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Open access Oct 2026

Syntaxin11 deficiency inhibits CRAC channel priming to suppress cytotoxicity and gene expression in T lymphocytes independent of membrane trafficking

It is shown that STX11 directly binds and regulates Orai1, the pore-forming subunit of calcium release-activated calcium (CRAC) channels, and ‘primes’ Orai1 for optimal on-site multimeric assembly, which was Stim independent but required for gating.

Sritama Datta, Abhikarsh Gupta, K. M. Jagetiya et al. · eLife · 0 citations

Open access Sep 2026

Semi-synthesis of the C-terminal region of PfRALP1: an alternative strategy for producing a hard-to-express merozoite protein

Plasmodium falciparum rhoptry-associated leucine zipper-like protein 1 (PfRALP1) is an indispensable protein involved in merozoite invasion of human red blood cells (RBCs), leading to the deadly malaria disease. PfRALP1 is stored in the rhoptry neck of merozoites and translocated to the moving junction during invasion...

Akash Narayan, S. Raran-Kurussi, M. Bhattacharyya et al. · RSC Chemical Biology · 0 citations