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S. Reichow

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Open access Aug 2026

Multi-ion permeation and dynamic conductance modulation in connexin gap junction channels

Gap junction channels formed by connexins mediate direct intercellular communication and are essential for electrical signaling and tissue homeostasis. Despite their large, solvent-accessible pores, connexin channels exhibit distinct conductance, selectivity, and rectification properties, but the molecular mechanisms u...

Bassam G. Haddad, Daniel M. Zuckerman, S. Reichow · 0 citations

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