Open access
Sep 2026
PRMT7 restricts CD8+ T cells expansion via the NF-ΚB pathway
Successful cellular immunotherapy for cancer utilising cytotoxic T lymphocytes (CTL) requires efficient expansion while maintaining effector function. Understanding how CTL expansion and function are regulated during the cell preparation process is thus important. Here, we show that T cell-specific deletion of Prmt7 us...
Nivine Srour, Kai-Xiu Luo, D. Allard et al.
· Nature Communications · 0 citations