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Author

S. Ripke

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Open access Aug 2026

Psychometric validation of research domain criteria, general health, and clinical-psychosocial parts of the minimum dataset of the German Center for Mental Health—informing a Delphi process

This study evaluated the latent structure and conceptual validity of the Research Domain Criteria (RDoC), General Health, and Clinical/Psychosocial clusters of the German Center for Mental Health (DZPG) Minimum Data Set (MDS). It aimed to determine whether these clusters represent interpretable constructs and demonstra...

Bernd R. Förstner, S. Böttger, Timm Seegert et al. · 0 citations
Aug 2026

Distinguishing different psychiatric disorders using DDx-PRS

Despite great progress on case–control polygenic prediction, an unmet need remains for a method that genetically distinguishes clinically related disorders (e.g., schizophrenia (SCZ) versus bipolar disorder (BIP) versus major depressive disorder (MDD) versus controls). We introduce differential diagnosis–polygenic risk...

W. Peyrot, G. Panagiotaropoulou, L. O. Olde Loohuis et al. · 0 citations

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