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Author

S. Rooijakkers

2 papers indexed here

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Review Open access Aug 2026

Complement-dependent phagocytosis in the clearance of various cellular targets.

Phagocytosis is the process of recognition and uptake of cells or large cellular debris; this process contributes to the removal of pathogens, cancerous cells and dead cells from the human body. Phagocytosis is greatly enhanced by the deposition of opsonins on the target cells, which act as a bridge between the target...

M. Blanter, Max L. B. Grönloh, P. E. Marques et al. · 0 citations
Open access Sep 2026

Identification of a C3b-specific nanobody that does not bind C3 and blocks alternative pathway convertases

The human complement system is a protein network in blood and other body fluids that fights invading pathogens and is involved in maintaining homeostasis. A central step in the complement cascade is the conversion of complement protein C3 to C3b by convertase enzymes. Upon cleavage of C3, the nascent C3b molecule under...

Eva M. Struijf, B. Bardoel, Joanne E. van Keulen et al. · 0 citations

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