S. S. Sahay

PIFA-mediated chemo-divergent esterification reaction: access to the synthesis of α-ketoesters and esters from sulfoxonium ylides.

Herein, we report a facile PIFA (bis(trifluoroacetoxy)iodobenzene)-mediated chemo-divergent synthesis of α-ketoesters and simple esters using sulfoxonium ylides and alcohols under mild and metal-free reaction conditions. Sulfoxonium ylides bearing electron-donating groups predominantly afforded α-ketoesters via the dir...