Author

S. Schulze

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Open access Oct 2026

Targeting Fibrotic Scars with Extracellular Vesicles Extracted from Mature Aloe vera Gel: Enhanced Antioxidant, Anti-inflammatory, and Antifibrotic Activity through M2 Macrophage Polarization and Inhibition of Myofibroblast Differentiation

Background Abnormal scarring and fibrotic skin disorders arise from dysregulated wound healing. While Aloe vera is widely recognized for its therapeutic properties, the potential of its extracellular vesicles (Av-EVs) remains underexplored. Objective To isolate and characterize Av-EVs and evaluate their antioxidant, an...

M. C. Ceballos-Santa, Janitri Venkatachala Babu, T. Gaborski et al. · bioRxiv · 0 citations

Open access Aug 2026

ProtPen Combines Sequence- and Structure-based Approaches to Facilitate Protein Function Predictions on a Proteome-wide Scale.

ProtPen is an open-source pipeline that facilitates protein function prediction by combining eggNOG-mapper for sequence-based annotation with Foldseek for rapid structural similarity searches using AlphaFold-predicted protein structures to facilitate the systemwide annotation of proteins of unknown function from proteo...

Diya Mathai, S. Schulze · Journal of Proteome Research · 0 citations

Open access Jul 2026

ProtPen combines sequence- and structure-based approaches to facilitate protein function predictions on a proteome-wide scale

ProtPen is an open-source pipeline that facilitates protein function prediction by combining eggNOG-mapper for sequence-based annotation with Foldseek for rapid structural similarity searches using AlphaFold-predicted protein structures and is readily extensible to incorporate additional protein function prediction too...

Diya Mathai, S. Schulze · bioRxiv · 0 citations