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Author

S. Story

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Aug 2026

Activity of Thiourea-Linked Diamidines against Multidrug-Resistant Staphylococcus aureus.

Staphylococcus aureus is a leading cause of antibiotic-resistant infections worldwide. Therefore, there is a constant need to develop new growth inhibitors. Pentamidine analogs (PAs) composed of thiourea-linked amidines were evaluated for activity against methicillin-resistant S. aureus (MRSA) and other Gram-positive b...

Yi Jin, S. Story, J. Chamberlin et al. · 0 citations
Aug 2026

Tobramycin-Peptide Nucleic Acids Synergize with Polymyxin B and Other Bioactive Compounds to Inhibit Growth of Gram-Negative Bacteria

Resistance studies demonstrate that the TOB-PNA conjugate, both alone and in combination with PMB, maintains antibacterial activity over prolonged exposure, suggesting a higher barrier to resistance evolution than conventional TOB treatment.

S. Story, Sarah L. Wicks, Sayantan Bhaduri et al. · 0 citations

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