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S. Surojit

2 papers indexed here

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Open access Sep 2026

MyD88 deficiency modestly attenuates disease in a Leigh syndrome mouse model while enrofloxacin accelerates disease.

Primary genetic mitochondrial diseases (GMDs) are clinically and genetically diverse diseases. Leigh syndrome (LS), the most common pediatric presentation of GMD is a severe progressive multi-system disorder with diverse manifestations. No effective treatments currently exist. Recent data from the Ndufs4(-/-) LS mouse...

Allison R. Hanaford, Elizaveta A. Olkhova, Ryan W. Liao et al. · 0 citations
Open access Aug 2026

Immune profiling and treatment cessation provide mechanistic insights into disease pathogenesis and considerations for translating pre-clinical strategies in Leigh syndrome

Genetic mitochondrial diseases (GMDs) are major challenges to human health accounting for a significant fraction of heritable neurologic diseases, myopathies, and inborn errors of metabolism. Leigh syndrome (LS) is the most common clinical presentation of GMD in pediatric patients. LS is a severe and complex disease fo...

Elizaveta A. Olkhova, E. Kayser, A. Dimitriou et al. · 0 citations

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