S. Sydlik

Engineering the interface: pH-dependent self-assembly of lysine-tyrosine synthetic copolypeptides for anti-biofilm implant coatings.

Developing resilient antimicrobial coatings for medical implants requires a sophisticated balance between direct bactericidal activity and resistance to bacterial adhesion. While poly(L-lysine) provides effective membrane disruption, its performance is often compromised by the accumulation of cellular debris, which fac...