Five polyphenolic compounds formed stable interactions with RdRp, as indicated by RMSD, RMSF, interaction energy, and radius of gyration analyses, and warrant further in vitro and in vivo evaluation as candidate SARS-CoV-2 RdRp inhibitors.
Willy Wijayanti, N. Yuliana, Endang Prangdimurti et al.· Jurnal Jamu Indonesia· 0 citations
Pyranoamentoflavone compounds found in nyamplung, 5,3',5'-Trihydroxy-6,7,4'-trimethoxyflavone in kemuning, and Sotetsuflavone in jamb antidote have good potential as an FGF2 inhibitor as an anti-cancer drug for Glioblastoma.
N. Fernando, Agus Kartono, S. T. Wahyudi· Jurnal Ilmiah Berkala Sains...· 0 citations
Mangostanol and 9-hydroxycalabaxanthone will be prioritized for in vitro/in vivo testing, underscoring the importance of a stepwise, structure-based approach to identify plant-based natural compounds targeting XIAP-BIR3.
S. Hodijah, Agus Kartono, Zahra Silmi Muscifah et al.· Indonesian Journal of Chemis...· 0 citations
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