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Nov 2026

AAV-mediated expression of a SARS-CoV-2 neutralizing antibody in monocyte-derived dendritic cells and human airway epithelial cells.

AAV6.2FF is qualified as a promising platform for localized mAb expression in the human respiratory tract for adeno-associated virus (AAV) vectors to enable full mAb expression in human respiratory cell subsets.

Maureen Obara, Aparna Shandheep, Katharina Rahmel-Stein et al. · 0 citations
Open access Oct 2026

Basal Cell Expansion Conditions Influence Differentiation and Phenotypic Outcomes in Primary Nasal Epithelia Grown at Air–Liquid Interface

Background/Objectives: Primary airway epithelia grown at air–liquid interface (ALI) are widely used to model respiratory endophenotypes and to enable individualized functional testing. However, culture conditions used to establish ALI vary considerably and may introduce selection biases. We aimed to adapt our lung expl...

S. Tamm, R. Dalferth, Long-Hua Feng et al. · 0 citations

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