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S. Tantravahi

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Open access Jul 2026

Single agent selinexor is active in patients with myelofibrosis refractory or intolerant to JAK inhibitors

Myelo fi brosis (MF) is caused by expansion of mutated hematopoietic stem and progenitor cells that results in bone marrow (BM) fi brosis, ineffective erythropoiesis, elevated in fl am-matory cytokines, and extramedullary hematopoiesis. Most MF patients experience constitutional symptoms that impair quality of life. Cytop...

S. Tantravahi, Andrea A Ellero, Ami B. Patel et al. · 1 citation

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