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Open access Oct 2026

Eggshell-Templated Mn-Doped Hydroxyapatite Composite Scaffold: Coupling ROS Scavenging with Piezo1 Activation for Bone Regeneration

The treatment of critical-sized bone defects remains challenging due to immune microenvironment dysregulation characterized by excessive ROS, persistent inflammation, and apoptosis, which impede tissue regeneration. Conventional biomaterials often overlook the unique structure and composition of natural materials. He...

Meng-Qi Zhao, Jing-Yang Cheng, Hui Zheng et al. · 0 citations
Open access Aug 2026

Developing Multimodal Cu-TCP@PCL Periosteal Patch with Modulated Morphogenesis and Osteogenic Enhancement for Bone Tissue-Engineering Application

A hierarchical scaffold serving as a tissue-engineered periosteum (TEPO) via modular layer-by-layer assembly for bone repair and demonstrates the integrated performance of the TEPO in modulating cell alignment and promoting osteogenic differentiation in vitro.

Wanqi Zhang, Shi-Hui Xiong, Hoi Pan Harry Cheung et al. · 0 citations

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