S. Theurer

Tumor-associated neutrophils and macrophages differentially affect T cell biology in the head and neck cancer tumor microenvironment.

Intra-tumoral T cell activity is required for effective anti-tumor immune responses and is partly regulated by tumor-associated neutrophils and macrophages. Here, we investigated the spatial context of neutrophil/macrophage interactions with CD8+ T cells in head and neck squamous cell carcinoma. Using multiplex immunof...

Incidence and Survival Trends in Cancer of Unknown Primary (CUP): An Analysis From the North Rhine-Westphalia Cancer Registry, 2007-2023.

Clinical Outcomes of Pembrolizumab Combination Therapy in Heavily Pretreated PDTC and Anaplastic Thyroid Cancer.

BACKGROUND Poorly differentiated (PDTC) and anaplastic thyroid carcinoma (ATC) are rare, aggressive malignancies with limited treatment options. Although targeted therapies for tumours harbouring BRAF V600E mutations or fusions involving NTRK1, NTRK2, NTRK3, or RET have expanded treatment options, most patients lack su...