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S. Tomiyasu

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Open access Oct 2026

Adeno-associated virus-mediated epithelial IL-33 silencing attenuates type 2 airway inflammation.

BACKGROUND While therapeutic strategies targeting the IL-33/ST2 axis are under active development, systemic blockade of IL-33 raises concerns because of its pleiotropic and protective functions in multiple organs. Therefore, strategies enabling cell- and tissue-specific control of IL-33 are needed. METHODS We develop...

S. Tomiyasu, H. Kabata, Yuto Akiyama et al. · 0 citations

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