Sleep and circadian disturbances are associated with cognitive decline and dementia. Narcolepsy type 1 (NT1), characterized by severe sleep-wake disruption and loss of hypocretin, would therefore be expected to predispose individuals to premature brain aging. Yet available biomarker and neuroimaging findings do not con...
Renata K. Carvalho, T. Alvarenga, F. Coelho et al.· Ageing Research Reviews· 0 citations
Obesity and sleep disturbances are highly prevalent chronic conditions that share multiple pathophysiological mechanisms, including chronic low-grade inflammation, neuroendocrine dysfunction, circadian misalignment, autonomic imbalance, insulin resistance, and metabolic dysregulation. These conditions establish a multi...
Raquel M. S. Campos, H. de Sá Souza, Carolina Machado Favaron et al.· Frontiers in sleep· 0 citations
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